Welcome to Prof. Junho Chung's Laboratory





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Recent publications (2019 & 2018)


Shin JW, Kim S, Ha S, Choi B, Kim S, Im SA, Yoon TY, Chung J. The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab. Biomolecules. 2019 Oct 19;9(10). doi: 10.3390/biom9100629. PubMed PMID: 31635022.


Kim SI, Kim S, Kim J, Chang SY, Shim JM, Jin J, Lim C, Baek S, Min JY, Park WB, Oh MD, Kim S, Chung J. Generation of a Nebulizable CDR-Modified MERS-CoV Neutralizing Human Antibody. Int J Mol Sci. 2019 Oct 12;20(20). doi: 10.3390/ijms20205073. PubMed PMID: 31614869.


Kim H, Kim B, Il Kim S, Kim H, Ryu B, Chung J, Lee Z, Kim H. S100A4 released from highly bone-metastatic breast cancer cells plays a critical role in osteolysis. Bone Research. 2019/09; 7(1):30. doi: 10.1038/s41413-019-0068-5.


Park S, Lee JG, Jang JY, Ryu JH, Kim DJ, Chang SJ, Kim H, Chung J, West L, Yang J. Induction of Accommodation by Anti-complement Component 5 Antibody-based Immunosuppression in ABO-incompatible Heart Transplantation. Transplantation. 2019 Sep;103(9):e248-e255. doi: 10.1097/TP.0000000000002808. PubMed PMID: 31461745.


Kim S, Kim H, Jo DH, Kim JH, Kim SR, Kang D, Hwang D, Chung J. Corrigendum to "Bispecific anti-mPDGFRβ x cotinine scFv-Cκ-scFv fusion protein and cotinine-duocarmycin can form antibody-drug conjugate-like complexes that exert cytotoxicity against mPDGFRβ expressing cells" [Methods 154 (2019) 125-135]. Methods. 2019 Jul 15;164-165:122. doi: 10.1016/j.ymeth.2019.07.011. Epub 2019 Jul 15. PubMed PMID: 31320194.


Sueoka E, Watanabe T, Mashima T, Shirakami Y, Komori A, Matsuo K, Yoshikawa HY, Cho KA, Park TJ, Seimiya H, Kim EG, Suganuma M, Chung J. Meeting report of the 14th Japan-Korea joint symposium on cancer and aging research: current status of translational research and approaches to precision medicine. J Cancer Res Clin Oncol. 2019 May;145(5):1263-1271. doi: 10.1007/s00432-019-02887-2. Epub 2019 Mar 11. PubMed PMID: 30859317.


Noh J, Kim O, Jung Y, Han H, Kim JE, Kim S, Lee S, Park J, Jung RH, Kim SI, Park J, Han J, Lee H, Yoo DK, Lee AC, Kwon E, Ryu T, Chung J, Kwon S. High-throughput retrieval of physical DNA for NGS-identifiable clones in phage display library. MAbs. 2019 Apr;11(3):532-545. doi: 10.1080/19420862.2019.1571878. Epub 2019 Feb 12. PubMed PMID: 30735467; PubMed Central PMCID: PMC6512904.


Yu B, Hwang D, Jeon H, Kim H, Lee Y, Keum H, Kim J, Lee DY, Kim Y, Chung J, Jon S. A Hybrid Platform Based on a Bispecific Peptide-Antibody Complex for Targeted Cancer Therapy. Angew Chem Int Ed Engl. 2019 Feb 11;58(7):2005-2010. doi: 10.1002/anie.201811509. Epub 2019 Jan 25. PubMed PMID: 30600870.


Kim KH, Kim J, Ko M, Chun JY, Kim H, Kim S, Min JY, Park WB, Oh MD, Chung J. An anti-Gn glycoprotein antibody from a convalescent patient potently inhibits the infection of severe fever with thrombocytopenia syndrome virus. PLoS Pathog. 2019 Feb;15(2):e1007375. doi: 10.1371/journal.ppat.1007375. eCollection 2019 Feb. PubMed PMID: 30707748; PubMed Central PMCID: PMC6380599.


Kim S, Kim H, Jo DH, Kim JH, Kim SR, Kang D, Hwang D, Chung J. Bispecific anti-mPDGFRβ x cotinine scFv-Cκ-scFv fusion protein and cotinine-duocarmycin can form antibody-drug conjugate-like complexes that exert cytotoxicity against mPDGFRβ expressing cells. Methods. 2019 Feb 1;154:125-135. doi: 10.1016/j.ymeth.2018.10.002. Epub 2018 Oct 4. PubMed PMID: 30292795.


Kim S, Lee H, Noh J, Lee Y, Han H, Yoo DK, Kim H, Kwon S, Chung J. Efficient Selection of Antibodies Reactive to Homologous Epitopes on Human and Mouse Hepatocyte Growth Factors by Next-Generation Sequencing-Based Analysis of the B Cell Repertoire. Int J Mol Sci. 2019 Jan 18;20(2). doi: 10.3390/ijms20020417. PubMed PMID: 30669409; PubMed Central PMCID: PMC6359367.


Kim H, Hwang D, Choi M, Lee S, Kang S, Lee Y, Kim S, Chung J, Jon S. Antibody-Assisted Delivery of a Peptide-Drug Conjugate for Targeted Cancer Therapy. Mol Pharm. 2019 Jan 7;16(1):165-172. doi: 10.1021/acs.molpharmaceut.8b00924. Epub 2018 Dec 17. PubMed PMID: 30521347.


Jin J, Park G, Park JB, Kim S, Kim H, Chung J. An anti-EGFR × cotinine bispecific antibody complexed with cotinine-conjugated duocarmycin inhibits growth of EGFR-positive cancer cells with KRAS mutations. Exp Mol Med. 2018 May 24;50(5):67. doi: 10.1038/s12276-018-0096-z. PubMed PMID: 29795377; PubMed Central PMCID: PMC5967348.


Kang CK, Choi SJ, Koh J, Jeon YK, Kim KH, Chung J, Choe PG, Kim NJ, Park WB, Oh MD. 18F-FDG PET and histopathologic findings in a patient with severe fever with thrombocytopenia syndrome. Ticks Tick Borne Dis. 2018 May;9(4):972-975. doi: 10.1016/j.ttbdis.2018.03.030. Epub 2018 Mar 28. PubMed PMID: 29615316.


Lee HW, Choi B, Kang HN, Kim H, Min A, Cha M, Ryu JY, Park S, Sohn J, Shin K, Yun MR, Han JY, Shon MJ, Jeong C, Chung J, Lee SH, Im SA, Cho BC, Yoon TY. Profiling of protein-protein interactions via single-molecule techniques predicts the dependence of cancers on growth-factor receptors. Nat Biomed Eng. 2018 Apr;2(4):239-253. doi: 10.1038/s41551-018-0212-3. Epub 2018 Apr 2. PubMed PMID: 30936439.


Shin JW, Kim SI, Yoon A, Jin J, Park HB, Kim H, Chung J. The Versatility of Framework Regions of Chicken VH and VL to Mutations. Immune Netw. 2018 Apr;18(2):e3. doi: 10.4110/in.2018.18.e3. eCollection 2018 Apr. PubMed PMID: 29732232; PubMed Central PMCID: PMC5928418.


Jin J, Park C, Cho SH, Chung J. The level of decoy epitope in PCV2 vaccine affects the neutralizing activity of sera in the immunized animals. Biochem Biophys Res Commun. 2018 Feb 12;496(3):846-851. doi: 10.1016/j.bbrc.2018.01.141. Epub 2018 Jan 31. PubMed PMID: 29374509.


Last Update: 29 Oct 2019