Welcome to Prof. Junho Chung's Laboratory





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Recent publications (2021 - 2019)


Kim SI, Noh J, Kim S, Choi Y, Yoo DK, Lee Y, Lee H, Jung J, Kang CK, Song KH, Choe PG, Kim HB, Kim ES, Kim NJ, Seong MW, Park WB, Oh MD, Kwon S, Chung J. Stereotypic neutralizing VH antibodies against SARS-CoV-2 spike protein receptor binding domain in COVID-19 patients and healthy individuals. Sci Transl Med. 2021 Jan 4;. doi: 10.1126/scitranslmed.abd6990. [Epub ahead of print] PubMed PMID: 33397677.


Chang S, Kim S, Han J, Ha S, Lee H, Song SW, Lee D, Kwon S, Chung J, Kim J. A High-Throughput Single-Clone Phage Fluorescence Microwell Immunoassay and Laser-Driven Clonal Retrieval System. Biomolecules. 2020 Mar 29;10(4). doi: 10.3390/biom10040517. PubMed PMID: 32235304; PubMed Central PMCID: PMC7226094.


Zalles M, Smith N, Saunders D, Saran T, Thomas L, Gulej R, Lerner M, Fung KM, Chung J, Hwang K, Jin J, Battiste J, Towner RA. Assessment of an scFv Antibody Fragment Against ELTD1 in a G55 Glioblastoma Xenograft Model. Transl Oncol. 2020 Mar;13(3):100737. doi: 10.1016/j.tranon.2019.12.009. Epub 2020 Mar 21. PubMed PMID: 32208341; PubMed Central PMCID: PMC7090355.


Kang JG, Jeon K, Choi H, Kim Y, Kim HI, Ro HJ, Seo YB, Shin J, Chung J, Jeon YK, Kim YS, Lee KH, Cho NH. Vaccination with single plasmid DNA encoding IL-12 and antigens of severe fever with thrombocytopenia syndrome virus elicits complete protection in IFNAR knockout mice. PLoS Negl Trop Dis. 2020 Mar;14(3):e0007813. doi: 10.1371/journal.pntd.0007813. eCollection 2020 Mar. PubMed PMID: 32196487; PubMed Central PMCID: PMC7112229.


Yoo DK, Lee SR, Jung Y, Han H, Lee HK, Han J, Kim S, Chae J, Ryu T, Chung J. Machine Learning-Guided Prediction of Antigen-Reactive In Silico Clonotypes Based on Changes in Clonal Abundance through Bio-Panning. Biomolecules. 2020 Mar 8;10(3). doi: 10.3390/biom10030421. PubMed PMID: 32182714; PubMed Central PMCID: PMC7175295.


Lee SH, Soh H, Chung JH, Cho EH, Lee SJ, Ju JM, Sheen JH, Kim H, Oh SJ, Lee SJ, Chung J, Choi K, Kim SY, Ryu JS. Feasibility of real-time in vivo 89Zr-DFO-labeled CAR T-cell trafficking using PET imaging. PLoS One. 2020;15(1):e0223814. doi: 10.1371/journal.pone.0223814. eCollection 2020. PubMed PMID: 31910217; PubMed Central PMCID: PMC6946129.


Zalles M, Smith N, Ziegler J, Saunders D, Remerowski S, Thomas L, Gulej R, Mamedova N, Lerner M, Fung KM, Chung J, Hwang K, Jin J, Wiley G, Brown C, Battiste J, Wren JD, Towner RA. Optimized monoclonal antibody treatment against ELTD1 for GBM in a G55 xenograft mouse model. J Cell Mol Med. 2020 Jan;24(2):1738-1749. doi: 10.1111/jcmm.14867. Epub 2019 Dec 21. PubMed PMID: 31863639; PubMed Central PMCID: PMC6991683.


Shin JW, Kim S, Ha S, Choi B, Kim S, Im SA, Yoon TY, Chung J. The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab. Biomolecules. 2019 Oct 19;9(10). doi: 10.3390/biom9100629. PubMed PMID: 31635022; PubMed Central PMCID: PMC6843359.


Kim SI, Kim S, Kim J, Chang SY, Shim JM, Jin J, Lim C, Baek S, Min JY, Park WB, Oh MD, Kim S, Chung J. Generation of a Nebulizable CDR-Modified MERS-CoV Neutralizing Human Antibody. Int J Mol Sci. 2019 Oct 12;20(20). doi: 10.3390/ijms20205073. PubMed PMID: 31614869; PubMed Central PMCID: PMC6829326.


Kim H, Kim B, Il Kim S, Kim HJ, Ryu BY, Chung J, Lee ZH, Kim HH. S100A4 released from highly bone-metastatic breast cancer cells plays a critical role in osteolysis. Bone Res. 2019;7:30. doi: 10.1038/s41413-019-0068-5. eCollection 2019. PubMed PMID: 31667000; PubMed Central PMCID: PMC6804941.



Park S, Lee JG, Jang JY, Ryu JH, Kim DJ, Chang SJ, Kim H, Chung J, West L, Yang J. Induction of Accommodation by Anti-complement Component 5 Antibody-based Immunosuppression in ABO-incompatible Heart Transplantation. Transplantation. 2019 Sep;103(9):e248-e255. doi: 10.1097/TP.0000000000002808. PubMed PMID: 31461745.


Kim S, Kim H, Jo DH, Kim JH, Kim SR, Kang D, Hwang D, Chung J. Corrigendum to "Bispecific anti-mPDGFRβ x cotinine scFv-Cκ-scFv fusion protein and cotinine-duocarmycin can form antibody-drug conjugate-like complexes that exert cytotoxicity against mPDGFRβ expressing cells" [Methods 154 (2019) 125-135]. Methods. 2019 Jul 15;164-165:122. doi: 10.1016/j.ymeth.2019.07.011. Epub 2019 Jul 15. PubMed PMID: 31320194.


Sueoka E, Watanabe T, Mashima T, Shirakami Y, Komori A, Matsuo K, Yoshikawa HY, Cho KA, Park TJ, Seimiya H, Kim EG, Suganuma M, Chung J. Meeting report of the 14th Japan-Korea joint symposium on cancer and aging research: current status of translational research and approaches to precision medicine. J Cancer Res Clin Oncol. 2019 May;145(5):1263-1271. doi: 10.1007/s00432-019-02887-2. Epub 2019 Mar 11. PubMed PMID: 30859317.


Noh J, Kim O, Jung Y, Han H, Kim JE, Kim S, Lee S, Park J, Jung RH, Kim SI, Park J, Han J, Lee H, Yoo DK, Lee AC, Kwon E, Ryu T, Chung J, Kwon S. High-throughput retrieval of physical DNA for NGS-identifiable clones in phage display library. MAbs. 2019 Apr;11(3):532-545. doi: 10.1080/19420862.2019.1571878. Epub 2019 Feb 12. PubMed PMID: 30735467; PubMed Central PMCID: PMC6512904.


Yu B, Hwang D, Jeon H, Kim H, Lee Y, Keum H, Kim J, Lee DY, Kim Y, Chung J, Jon S. A Hybrid Platform Based on a Bispecific Peptide-Antibody Complex for Targeted Cancer Therapy. Angew Chem Int Ed Engl. 2019 Feb 11;58(7):2005-2010. doi: 10.1002/anie.201811509. Epub 2019 Jan 25. PubMed PMID: 30600870.


Kim KH, Kim J, Ko M, Chun JY, Kim H, Kim S, Min JY, Park WB, Oh MD, Chung J. An anti-Gn glycoprotein antibody from a convalescent patient potently inhibits the infection of severe fever with thrombocytopenia syndrome virus. PLoS Pathog. 2019 Feb;15(2):e1007375. doi: 10.1371/journal.ppat.1007375. eCollection 2019 Feb. PubMed PMID: 30707748; PubMed Central PMCID: PMC6380599.


Kim S, Kim H, Jo DH, Kim JH, Kim SR, Kang D, Hwang D, Chung J. Bispecific anti-mPDGFRβ x cotinine scFv-Cκ-scFv fusion protein and cotinine-duocarmycin can form antibody-drug conjugate-like complexes that exert cytotoxicity against mPDGFRβ expressing cells. Methods. 2019 Feb 1;154:125-135. doi: 10.1016/j.ymeth.2018.10.002. Epub 2018 Oct 4. PubMed PMID: 30292795.


Kim S, Lee H, Noh J, Lee Y, Han H, Yoo DK, Kim H, Kwon S, Chung J. Efficient Selection of Antibodies Reactive to Homologous Epitopes on Human and Mouse Hepatocyte Growth Factors by Next-Generation Sequencing-Based Analysis of the B Cell Repertoire. Int J Mol Sci. 2019 Jan 18;20(2). doi: 10.3390/ijms20020417. PubMed PMID: 30669409; PubMed Central PMCID: PMC6359367.


Kim H, Hwang D, Choi M, Lee S, Kang S, Lee Y, Kim S, Chung J, Jon S. Antibody-Assisted Delivery of a Peptide-Drug Conjugate for Targeted Cancer Therapy. Mol Pharm. 2019 Jan 7;16(1):165-172. doi: 10.1021/acs.molpharmaceut.8b00924. Epub 2018 Dec 17. PubMed PMID: 30521347.

Last Update: 25 Jan  2021