Publications
Sunyoung Park, Do-Hoon Lee, Jae-Gahb Park, Yong Tae Lee and
Junho Chung. A Highly Sensitive Enzyme Immunoassay for
Measuring Cotinine in Passive Smokers Clinica Chimica Acta. 2010
Apr 26. Accepted.


Sumin Yoon, Yong-sung Kim, Hyunbo Shim, and Junho Chung.
Current Perspectives on Therapeutic Antibodies Biotechnology and
Bioprocess Engineering. 2010 Apr 12 Accepted.

Choi YS, Kim HB, Chung J, Kim HS, Yi JH, Park JK. Preclinical
Analysis of Irreversible Electroporation on Rat Liver Tissues Using a
Microfabricated Electroporator Tissue Eng Part C Methods. 2010
Apr 6. [Epub ahead of print] PMID: 20192718


Yeom HJ, Shin KJ, Kim JS, Kim SJ, Lee SM, Paul S, Han JW, Ahn
CR, Seong JK, Chung JH, Hwang SY. Porcine Aortic Endothelial Cell
Genes Responsive to Selected Inflammatory Stimulators J Vet Med
Sci. 2009 Nov;71(11):1499-508. PMID:19959902


Oh IS, Lee JC, Lee MS, Chung JH, Kim DM. Cell-free production
of  functional antibody fragments. Bioprocess Biosyst Eng 2009 Aug
23. [Epub ahead of print] PMID:19701777


Kim YG, Jeong HJ, Jang KS, Yang YH, Song YS, Chung J, Kim BG.
Rapid and high-throughput analysis of N-glycans from ovarian
cancer serum using a 96-well plate platform. Anal Biochem 2009 Aug
15;391(2):151-3. PMID:19457428


Kim M, Min HJ, Won HY, Park H, Lee JC, Park HW, Chung J,
Hwang ES, Lee K. Dimerization of translationally controlled tumor
protein is essential for its cytokine-like activity. PLoS One 2009 Jul
31;4(7):e6464. PMID:19649253


Kim YG, Gil GC, Jang KS, Lee S, Kim HI, Kim JS, Chung J, Park
CG, Harvey DJ, Kim BG. Qualitative and quantitative comparison of
N-glycans between pig endothelial and islet cells by high-
performance liquid chromatography and mass spectrometry-based
strategy. J Mass Spectrom 2009 Jul;44(7):1087-104 PMID:19373860


Park KJ, Lee SH, Lee CH, Jang JY, Chung J, Kwon MH, Kim YS.
Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and
p53 are involved in the JNK-mediated autophagic cell death. Biochem
Biophys Res Commun 2009 May 15;382(4):726-9. PMID: 19318089


Kim EM, Park EH, Cheong SJ, Chang ML, Kim DW, Jeong HJ, Lim
ST, Sohn MH, Kim K, Chung J. Characterization biodistribution and
small-animal SPECT of I-1
25-labeled c-Met binding peptide in mice
bearing c-Met receptor tyrosine kinase-positive tumor xenografts
Nucl Med Biol 2009 May;36(4):371-8. PMID:194230
04

Lee S, Ha IS, Kim JH, Park KS, Han KH, Kim SH, Chae YC, Kim
SH, Kim YH, Suh PG, Ryu SH, Kim JE, Bang K, Hwang JI, Yang J,
Park KW, Chung J, Ahn C. Hydrogen Peroxide-Induced VCAM-1
Expression in Pancreatic Islets and β-Cells Through Extracellular
Ca2+ Influx Transplantation 2008 Nov;86(9):1257-1266 PMID:
19005408

Cho AY, Shin KJ, Chung J, Oh SS A Sensitive Enzyme
Immunoassay for Amygdalin in Food Extracts Using a Recombinant
Antibody J Food Prot. 2008 Oct;71(10):2048-52. PMID: 18939751

Lee MS, Lee JC, Choi CY, Chung J Production and Characterization
of Monoclonal Antibody to Botulinum Neurotoxin type B Light Chain
by Phage display Hybridoma 2008 Feb;27(1):18-24 PMID: 18294072

Lee, S., Chung, J., Ha, I. S., Yi, K., Lee, J. E., Kang, H. K., Choi, I.,
Oh, K., Kim, J. Y., Surh, C. D., and Ahn, C. Hydrogen peroxide
increases human leukocyte adhesion to porcine aortic endothelial cells
via NFB-dependent upregulation of vascular cell adhesion
molecule-1 (VCAM-1): The functional significance of H2O2-induced
porcine VCAM-1. International Immunology. 2007. Dec; 19:1349-
1359 PMID: 17977815


Yi, K. S., Lee, S., Kang, Y., Bae, Y., Hwang, S. Y., Ha, I., Kim, H.,
Kim, M. S., Cho, B., Kang, H. J., Yang, J., Chung, J., and Ahn, C.
Weak response of porcine C5a receptor towards human C5a
Xenotransplantation. 2007 Nov;14(6):563-71 PMID: 17991144


Kim HK, Kim JE, Chung J, Park KH, Han KS, Cho HI. Lithium down-
regulates the expression of CXCR4 in human neutrophils. J Trace
Elem Med Biol. 2007;21(3):204-9. PMID: 17697959


Kim HK, Kim JE, Chung J, Han KS, Cho HI. Surface expression of
neutrophil CXCR4 is down-modulated by bacterial endotoxin. Int J
Hematol. 2007 Jun;85(5):390-6. PMID: 17562613


Rhim JH, Kim SA, Lee JE, Kim DJ, Chung HK, Shin KJ, Chung J.
Cancer cell-derived IL-1 induces IL-8 secretion in endothelial cells. J
Cancer Res Clin Oncol. 2008 Jan;134(1):45-50 PMID: 17622559


Ji-Chul Lee , Sun-Young Park , Cha-Yong Choi , Junho Chung , and
Myung-Shin Lee Generation of a Naive/synthetic Antibody Specific
to Botulinum Neurotoxin via Motif-grafting Biotechnol. Bioprocess
Eng. 2007 Jun 30, 12, 3:282-288

Kim HK, Kim JE, Chung J, Kim YT, Kang SH, Han KS, Cho HI.
Lipopolysaccharide down-regulates the thrombomodulin expression
of peripheral blood monocytes: effect of serum on thrombomodulin
expression in the THP-1 monocytic cell line. Blood Coagul
Fibrinolysis. 2007 Mar;18(2):157-164. PMID: 17287633

Kim K, Hur Y, Ryu EK, Rhim JH, Choi CY, Baek CM, Lee JH,
Chung J. A neutralizable epitope is induced on HGF upon its
interaction with its receptor cMet. Biochem Biophys Res Commun.  
2007 Mar 2;354(1):115-21.PMID: 17214965

Park SG, Jung YJ, Lee YY, Yang CM, Kim IJ, Chung JH, Kim IS,
Lee YJ, Park SJ, Lee JN, Seo SK, Park YH, Choi IH. Improvement
of Neutralizing Activity of Human scFv Antibodies Against Hepatitis
B Virus Binding Using CDR3 V(H) Mutant Library. Viral Immunol.
2006;19(1):115-23. PMID: 16553557

Kim YG, Kim SY, Hur YM, Joo HS, Chung J, Lee DS, Royle L,
Rudd PM, Dwek RA, Harvey DJ, Kim BG. The identification and
characterization of xenoantigenic nonhuman carbohydrate sequences
in membrane proteins from porcine kidney. Proteomics. 2006 Feb 9;
6 (4):1133-1142 PMID: 16470663

Yun-Gon Kim, Chang-Soo Lee, Woo-Jae Chung, Eun-Mi Kim, Dong-
Sik Shin, June-Hyung Kim, Yoon-Sik Lee, Junho Chung and Byung-
Gee Kim Selection of peptides for lipopolysaccharide binding on to
epoxy beads and selective detection of Gram-negative bacteria
Biotechnology Letters, 2006 Jan;28(2):79-84. PMID: 16369689

Im SY, Kim KS, Yun CO, Kim JH, Yi KS, Chung J. Generation of a
rabbit V(H) domain antibody polyspecific to c-Met and adenoviral
knob protein. Biochem Biophys Res Commun. 2006 Jan 6;339(1):
305-12. Epub 2005 Nov 15 PMID: 16298341


Heo MA, Kim SH, Kim SY, Kim YJ, Chung J, Oh MK, Lee SG.
Functional expression of single-chain variable fragment antibody
against c-Met in the cytoplasm of Escherichia coli. Protein Expr
Purif. 2005 Dec 28; PMID: 16414274

Youk HJ, Lee E, Choi MK, Lee YJ, Chung JH, Kim SH, Lee CH, Lim
SJ. Enhanced anticancer efficacy of alpha-tocopheryl succinate by
conjugation with polyethylene glycol. J Control Release. 2005 Sep
20; 107(1):43-52. PMID: 16081183


Ruyani A, Sudarwati S, Sutasurya LA, Sumarsono SH, Kim DJ,
Chung JH. Heat Shock Protein 70 is Up-Regulated in Mouse Forelimb
Bud by Methoxyacetic Acid treatment Birth Defects Research Part A:
Clinical and Molecular Teratology 2005 Jul;73(7):517-21. PMID:
15959878


Kim YG, Lee CS, Chung WJ, Kim EM, Shin DS, Rhim JH, Lee YS,
Kim BG, Chung J.  Screening of LPS-specific peptides from a phage
display library using epoxy beads. Biochem Biophys Res Commun.
2005 Apr 1;329(1):312-7. PMID: 15721308

Kwon YS, Chung J, Shin GT, Lee SY, Jang YJ. Variable region
genes of human monoclonal autoantibodies to histones H2A and H2B
from a systemic lupus erythematosus patient. Mol Immunol. 2005
Feb;42(3):311-7. PMID: 15589319


Yi KS, Chung J, Park KH, Kim K, Im SY, Choi CY, Im MJ, Kim UH.
Expression system for enhanced green fluorescence protein
conjugated recombinant antibody fragment. Hybrid Hybridomics.
2004 Oct;23(5):279-86. PMID: 15672605

Yoon SK, Lim NK, Ha SA, Park YG, Choi JY, Chung KW, Sun HS,
Choi MJ, Chung J, Wands JR, Kim JW. The human cervical cancer
oncogene protein is a biomarker for human hepatocellular carcinoma.
Cancer Res. 2004 Aug; 64 (15), 5434–5441. PMID: 15289352


Kim HK, Song KS, Chung JH, Lee KR, Lee SN. Platelet
microparticles induce angiogenesis in vitro. Br J Haematol. 2004 Feb;
124(3): 376-84. PMID: 14717787

Chung J, Rader C, Popkov M, Hur YM, Kim HK, Lee YJ, Barbas CF
3rd. Integrin αIIbβ3 specific synthetic human monoclonal antibodies
and HCDR3 peptides that potently inhibit platelet aggregation FASEB
J. 2004 Feb;18(2):361-3. Epub 2003 Dec 19 PMID: 14688205

Jendreyko N, Popkov M, Beerli RR, Chung J, McGavern DB, Rader
C, Barbas CF 3rd. Intra-diabodies: Bispecific, tetravalent antibodies
for the simultaneous functional knockout of two cell surface
receptors J Biol Chem. 2003 Nov 28;278(48):47812-9. Epub 2003
Aug 28. PMID: 12947084


Choi JW, Kim DJ, Rhim JH, Chung JH, Chung HK.Generation and
characterization of IgG monoclonal antibodies specific for
malondialdehyde. Hybrid Hybridomics. 2003 Aug;22(4):259-62.
PMID: 14511571


Kim HK, Song KS, Kim HO, Chung JH, Lee KR, Lee YJ, Lee DH,
Lee ES, Kim HK, Ryu KW, Bae JM. Circulating numbers of
endothelial progenitor cells in patients with gastric and breast cancer.
Cancer Lett. 2003 Jul 30;198(1):83-8. PMID: 12893434

Shin YK, Choi YL, Choi EY, Kim MK, Kook MC, Chung J, Choi YK,
Kim HS, Song HG, Park SH. Targeted cytotoxic effect of anti-JL1
immunotoxin against a human leukemic cell line and its clinical
implications. Cancer Immunol Immunother. 2003 Aug;52(8):506-12.
Epub 2003 May 27. PMID: 12768327


Chung J, Park S, Kim D, Rhim J, Kim I, Choi I, Yi K, Ryu S, Suh P,
Chung D, Bae Y, Shin Y, Park S. Identification of antigenic peptide
recognized by the anti-JL1 leukemia-specific monoclonal antibody
from combinatorial peptide phage display libraries. J Cancer Res Clin  
Oncol. 2002 Dec;128(12):641-9. Epub 2002 Nov 13. PMID:
12474050


Kim DJ, Chung JH, Ryu YS, Rhim JH, Kim CW, Suh Y, Chung HK.
Production and characterisation of a recombinant scFv reactive with
human gastrointestinal carcinomas. Br J Cancer. 2002 Aug 12;87(4):
405-13. PMID: 12177777


Shin JH, Chung J, Kim HO, Kim YH, Hur YM, Rhim JH, Chung HK,
Park SC, Park JG, Yang HK. Detection of cancer cells in peripheral
blood of stomach cancer patients using RT-PCR amplification of
tumour-specific mRNAs. Aliment Pharmacol Ther. 2002 Apr;16
Suppl 2:137-44. PMID: 11966534  

Yi KS, Chung JH, Lee YH, Chung HG, Kim IJ, Suh BC, Kim E,
Cocco L, Ryu SH, Suh PG. Inhibition of the EGF-induced activation
of phospholipase C-gamma1 by a single chain antibody fragment.
Oncogene. 2001 Nov 29;20(55):7954-64. PMID: 11753678

Park S, Lee B, Kim I, Choi I, Hong K, Ryu Y, Rhim J, Shin J, Park
SC, Chung H, Chung J. Immunobead RT-PCR versus regular RT-
PCR amplification of CEA mRNA in peripheral blood. J Cancer Res
Clin Oncol. 2001 Aug;127(8):489-94. PMID: 11501748


Shin YK, Choi EY, Kim SH, Chung J, Chung DH, Park WS, Jung
KC, Kim HS, Park S, Kim HJ, Park MH, Min CK, Kim CC, Park SH.
Expression of leukemia-associated antigen, JL1, in bone marrow and
thymus. Am J Pathol. 2001 Apr;158(4):1473-80. PMID: 11290565

Hong KM, Jang SJ, Kong G, Song KY, Park JG, Kim DJ, Chung JH,
Lee JH, Paik MK, Chung HK. A novel tumor-associated mucin of
gastrointestinal carcinoma. J Cancer Res Clin Oncol. 2001 Sep;127
(9):551-8. PMID: 11570576


Kim DJ, Chung JH, Lee JS, Moon YI, Seo JS, Chung HK.
Production and characterization of a monoclonal antibody specific to
the human 70-kDa heat shock protein. Hybridoma. 2000 Oct;19(5):
369-74. PMID: 11128026

Park SG, Lee JS, Je EY, Kim IJ, Chung JH, Choi IH. Affinity
maturation of natural antibody using a chain shuffling technique and
the expression of recombinant antibodies in Escherichia coli.
Biochem Biophys Res Commun. 2000 Aug 28;275(2):553-7. PMID:
10964702


Song MK, Oh MS, Lee JH, Lee JN, Chung JH, Park SG, Choi IH.
Light chain of natural antibody plays a dominant role in protein
antigen binding. Biochem Biophys Res Commun. 2000 Feb 16;268
(2):390-4. PMID: 10679214

Yi K, Chung J, Kim H, Kim I, Jung H, Kim J, Choi I, Suh P, Chung
H. Expression and characterization of anti-NCA-95 scFv (CEA 79
scFv) in a prokaryotic expression vector modified to contain a Sfi I
and Not I site. Hybridoma. 1999 Jun;18(3):243-9. PMID: 10475238

Choi IH, Park SG, Chung JH, Kim IJ, Hong HJ. Generation of human
Fab monoclonal antibodies against preS1 of hepatitis B virus using
repertoire cloning. Hybridoma. 1998 Dec;17(6):535-40. PMID:
9890709


Chung JH, Choi SJ, Kim HJ, Kim IJ, Choi IH, Lee SD, Yi KS, Suh
PG, Ryu SH, Chung HK. Cloning and characterization of cDNAs
encoding VH and VL of a monoclonal anti-CEA antibody (CEA 79)
cross-reactive with NCA-95 and generation of a single-chain Fv
molecule (scFv). Mol Cells. 1997 Dec 31;7(6):816-9. PMID: 9509426

Sin JI, Sung JH, Suh YS, Lee AH, Chung JH, Sung YC.  Protective
immunity against heterologous challenge with encephalomyocarditis
virus by VP1 DNA vaccination: effect of coinjection with a
granulocyte-macrophage colony stimulating factor gene. Vaccine.
1997 Dec;15(17-18):1827-33. PMID: 9413089


















Junho Chung's Laboratory